Introduction:
The fatality rate of the patients contaminated from deadly Covid-19 is at a rise. If necessary, precautions are not adopted then the situation will only get worse. From the data available till now nobody knows about the actual cause of the virus and nor the cure for it. In this situation of crisis, COVID-19 recombinant proteins can play a vital role in this battle of life for all humanity.
Within months of the outbreak of COVID-19, scientists, and researchers across the world are battling to develop a vaccine by using several techniques including DNA, recombinant protein, adenoviral vector, and mRNA. To develop a COVID-19 vaccine important information like target product profile, immunization route, production facility, finding target coronavirus antigen, target population, etc. are required.
What is a recombinant protein?
Recombinant protein or recombinant DNA is the protein that is produced artificially by combining the DNA from cells of different organisms. Proteins are manufactured inside our body naturally these protein helps us to remain fit and increase our immunity to fight from diseases. But, when deficiency of these proteins occurs in the body it is then fulfilled by some external source for instance ‘insulin’. Insulin is obtained from cow’s pancreas. These artificially produced proteins are called recombinant proteins. For producing these artificial proteins, we rely on the technology called RDT (Recombinant DNA technology). The idea behind this process is to produce a protein in large quantities to fulfill the immense need rapidly.
How Long Will It Take to develop a vaccine?
The development of a Vaccine is still at least one and a half years ahead. a vaccine can prevent infection and cease the contamination process. But it does take time in the development process of vaccines. Technology advanced in genomics has empowered researchers to walk at an extraordinary pace. The development of a vaccine is a costly and risky operation. Scientists have to research from scratch whenever a new virus outbreak occurs. It took 20 months for scientists and virologists to develop a vaccine when the 2003 SARS outbreak occurs. After the 2015 Zika outbreak, experts had brought the vaccine development time down to six months, ready for human trials.
Now the only hope is that research from previous outbreaks will help in reducing the vaccine timeline. Researchers have studied the current coronavirus genome discovered the proteins i.e. spike proteins that transmit infection. At least three companies are working in Australia at the National Institutes of Health scientists, on candidates for vaccines. The researchers have signaled that it may take months or even years to carry out initial trials testing at a large scale so that they can confirm if the vaccine is safe and effective or not. In the best case, a vaccine will be made available to the public a year from now.
Here are the critical questions that researchers are still pursuing:
• How to reduce the risk of infection?
• What are the signs of the infection?
• What precautions to be taken if you feel to be infected?
• How some of the nations responded effectively to the virus?
• What precautions are to be taken by doctors and healthcare personnel.
Evolution and identification of Virus:
The new COVID-19 virus that hopped at the end of last year has managed to create a worldwide emergency situation among scientists and the international community in just a few weeks. The epidemic is converted into pandemic within days.
With each new outbreak, many open questions will be addressed as the disease spreads and scientists continue to study the nature of the virus. The World Health Organization has declared an “international public health emergency” as the first person in the U.S. is confirmed of illness. As the virus continues to spread it is also changing it’s from. We can say it possesses the ability to adapt to any environment. For instance, in New Delhi, the capital of India random test of 736 patients has been conducted and out of which 186 are found to be infected. But what’s most concerning about them is that all of them are asymptomatic i.e. there are no signs or symptoms from which they can be identified. This is a very critical stage where we cannot identify without conducting a test that a person is infected or not. The infected person also did not get any idea about being infected. We at GeneMedi https://www.genemedi.net/ develops coronavirus recombinant protein to help scientist in this fight for humanity. So they can develop an effective vaccine.
How recombinant proteins can protect you from getting infected?
As discussed above recombinant protein are artificial proteins. These proteins act as a supplement for our body. It fulfills the deficiency of the protein if any in our body. It improves our immunity which in turn counteract the attack of the virus on human cell and protects us from getting effected from the diseases. Here at GeneMedi, we produce Recombinant COVID-19 antigen, coronavirus Spike Protein (RBD, C-mFC Tag). Developing these high-quality Coronavirus recombinant proteins we contribute to helping global scientists, virologists, and researchers for the development of drugs against 2019 novel coronavirus (SARS2 coronavirus).